Carbon Tetrachloride → 1-Benzyl-3,7-dichloro-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

Participants

Reaction Steps

A mixture of 1-benzyl-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester (60 mg, 0.202 mmol), NCS (57 mg, 0.424 mmol), and BzOOBz (2.4 mg, 0.01 mmol) in carbontetrachloride was refluxed for 1 hour. Then the reaction was cooled, solvent was removed, and the resulting residue was purified on column to give the title compound (48 mg). The title compound: ESI MS (m/z): 410 (M+H+).

Provenance & Evidence