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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642262Generated: November 1, 2026

Ethyl 2-((tert-butoxycarbonyl)amino)acetate → 2-[(tert-Butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1-phenyl-1H-indole-3-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-((tert-butoxycarbonyl)amino)acetateHCID 357729—
Reactant2-Bromomethyl-1-phenyl-1H-indole-3-carboxylic acid ethyl esterHCID 68427498—
Product2-[(tert-Butoxycarbonyl-ethoxycarbonylmethyl-amino)-methyl]-1-phenyl-1H-indole-3-carboxylic acid ethyl esterHCID 68428026—

Reaction Steps

Prepared in analogy to that of Example 1(c) from 2-bromomethyl-1-phenyl-1H-indole-3-carboxylic acid ethyl ester and tert-butoxycarbonylamino-acetic acid ethyl ester. The title compound, ESI MS (m/z): 503 (M+Na+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-a1b116258b2143d5842d32741b769568
Source noteuspto-grants-2010_04