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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642443Generated: October 31, 2026

Glycine → [(7-Cyano-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carbonyl)-amino]-acetic acid

https://huagongshe.com/reaction/642443

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
ReactantSodium methanolate methanolHCID 23694274—
Reactant7-Cyano-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68428708—
Product[(7-Cyano-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carbonyl)-amino]-acetic acidHCID 68427547—

Reaction Steps

Prepared in analogy to that of Example 1(e) from 7-cyano-4-hydroxy-1-phenyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 337 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-3c1f441f14b148f185c1e644359c9dcc
Source noteuspto-grants-2010_04