Glycine → HCID 68427906, compound

HRID 642447Notes

Reaction equation

HRID 642447 reaction equation
C(O[C:4]([C:6]1[C:7]([OH:23])=[C:8]2[CH:14]=[CH:13][N:12]([CH2:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:9]2=[CH:10][N:11]=1)=[O:5])C.[NH2:24][CH2:25][C:26]([OH:28])=[O:27].C[O-].[Na+].CO>>[OH:23][C:7]1[C:6]([C:4]([NH:24][CH2:25][C:26]([OH:28])=[O:27])=[O:5])=[N:11][CH:10]=[C:9]2[N:12]([CH2:15][CH2:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:13]=[CH:14][C:8]=12

Participants

4

Reactant 3

HCID 750GlycineHCID 23694274Sodium methanolate methanolHCID 68427996HCID 68427996, compound

Product 1

HCID 68427906HCID 68427906, compound

Procedure

Prepared in analogy to that of Example 1(e) from 4-hydroxy-1-phenethyl-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 340 (M+H)+.

Sources & evidence

ORD record
ord-1678bb9930834f878ae5e13b2b47ccbd
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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