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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642467Generated: October 28, 2026

Ammonium formate → 1-Benzyl-7-cyano-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium formateHCID 2723923—
Reactant1-Benzyl-2,3-dibromo-7-cyano-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68427528—
CatalystPalladiumHCID 23938—
Product1-Benzyl-7-cyano-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68427755—

Reaction Steps

Prepared in analogy to that of Example 6(a) from 1-benzyl-2,3-dibromo-7-cyano-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, ammonium formate and Pd/C. The title compound, ESI MS (m/z): 322 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-45fb1dc36a7a46ccb941e9ce0e50a762
Source noteuspto-grants-2010_04