HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine → [(1-Benzyl-3-bromo-7-cyano-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carbonyl)-amino]-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine | HCID 750 | — |
| Reactant | Sodium methanolate methanol | HCID 23694274 | — |
| Reactant | 4-Acetoxy-1-benzyl-3-bromo-7-cyano-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester | HCID 68428218 | — |
| Product | [(1-Benzyl-3-bromo-7-cyano-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carbonyl)-amino]-acetic acid | HCID 68428369 | — |
Reaction Steps
Prepared in analogy to that of Example 1(e) from 4-acetoxy-1-benzyl-3-bromo-7-cyano-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 429 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696223B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-e4fda86150e04af2b1f18d28c04fde88 |
| Source note | uspto-grants-2010_04 |