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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642477Generated: October 30, 2026

Glycine → {[7-Cyano-4-hydroxy-1-(4-methoxy-benzyl)-1H-pyrrolo[2,3-c]pyridine-5-carbonyl]-amino}-acetic acid

https://huagongshe.com/reaction/642477

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
ReactantSodium methanolate methanolHCID 23694274—
ReactantHCID 68428970HCID 68428970—
Product{[7-Cyano-4-hydroxy-1-(4-methoxy-benzyl)-1H-pyrrolo[2,3-c]pyridine-5-carbonyl]-amino}-acetic acidHCID 68427330—

Reaction Steps

Prepared in analogy to that of Example 1(e) from 7-cyano-4-hydroxy-1-(4-methoxy-benzyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 381 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-b54faae0fbe847a38ff18e8d6f716d31
Source noteuspto-grants-2010_04