HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → 2,3-Dibromo-1-(4-fluoro-phenyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | 2,3-Dibromo-4-hydroxy-1-(4-methoxy-phenyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester | HCID 68428780 | — |
| Product | 2,3-Dibromo-1-(4-fluoro-phenyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester | HCID 68427878 | — |
Reaction Steps
Prepared similarly according to a reaction sequence in Example 138 steps (a) and (b) for the synthesis of 2,3-dibromo-4-hydroxy-1-(4-methoxy-phenyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester starting from 4-fluoroaniline. The title compound, ESI MS (m/z): 457 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696223B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-069eb81049eb4174aea5b1e11fd3e81e |
| Source note | uspto-grants-2010_04 |