Glycine → HCID 68428222, compound

HRID 642514Notes

Reaction equation

HRID 642514 reaction equation
C(O[C:4]([C:6]1[C:7]([OH:24])=[C:8]2[CH:14]=[CH:13][N:12]([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([O:22][CH3:23])[CH:17]=3)[C:9]2=[CH:10][N:11]=1)=[O:5])C.[NH2:25][CH2:26][C:27]([OH:29])=[O:28].C[O-].[Na+].CO>>[OH:24][C:7]1[C:6]([C:4]([NH:25][CH2:26][C:27]([OH:29])=[O:28])=[O:5])=[N:11][CH:10]=[C:9]2[N:12]([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([O:22][CH3:23])[CH:17]=3)[CH:13]=[CH:14][C:8]=12

Participants

4

Reactant 3

HCID 750GlycineHCID 23694274Sodium methanolate methanolHCID 68427603HCID 68427603, compound

Product 1

HCID 68428222HCID 68428222, compound

Procedure

Prepared in analogy to that of Example 1(e) from 1-(3-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 356 (M+H)+.

Sources & evidence

ORD record
ord-e8cb69d94eed4ea6be9d1dc0c503879b
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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