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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642521Generated: October 31, 2026

2,3,7-Tribromo-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester → 2,3-Dibromo-7-cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester

https://huagongshe.com/reaction/642521

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3,7-Tribromo-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 86617375—
ReactantHCID 178418546HCID 178418546—
Product2,3-Dibromo-7-cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68427331—

Reaction Steps

Prepared in analogy to that of Example 105(a) from 2,3,7-tribromo-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester and CuCN. The title compound, ESI MS (m/z): 508 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-962c1e69db1c459687772831927a687f
Source noteuspto-grants-2010_04