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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642523Generated: November 4, 2026

Glycine → {[7-Cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carbonyl]-amino}-acetic acid

https://huagongshe.com/reaction/642523

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
ReactantSodium methanolate methanolHCID 23694274—
Reactant7-Cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68427003—
Product{[7-Cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carbonyl]-amino}-acetic acidHCID 68426287—

Reaction Steps

Prepared in analogy to that of Example 1(e) from 7-cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 381 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-7510fdcdaf404e58b92579c9f5f79a28
Source noteuspto-grants-2010_04