Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642533Generated: November 3, 2026

Glycine → {[1-(3-Fluoro-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carbonyl]-amino}-acetic acid

https://huagongshe.com/reaction/642533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
ReactantSodium methanolate methanolHCID 23694274—
Reactant1-(3-Fluoro-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl esterHCID 68426257—
Product{[1-(3-Fluoro-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carbonyl]-amino}-acetic acidHCID 68429612—

Reaction Steps

Prepared in analogy to that of Example 1(e) from 1-(3-fluoro-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester, glycine and NaOMe/HOMe. The title compound, ESI MS (m/z): 344 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696223B2
Source datasetuspto-grants-2010_04
ORD IDord-a66c778aaa7f4363b242c1a0a579830d
Source noteuspto-grants-2010_04