Ethyl 2-methyl-3-pyrrolecarboxylate → HCID 68428785, compound

HRID 642542Notes

Reaction equation

HRID 642542 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[CH:9][NH:8][C:7]=1[CH3:11])=[O:5])[CH3:2].[F:12][C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][C:20]=1[F:21])[CH2:16]Br>>[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[CH:9][N:8]([CH2:16][C:15]2[CH:18]=[CH:19][C:20]([F:21])=[C:13]([F:12])[CH:14]=2)[C:7]=1[CH3:11])=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 136747Ethyl 2-methyl-3-pyrrolecarboxylateHCID 5814364-(Bromomethyl)-1,2-difluorobenzene

Product 1

HCID 68428785HCID 68428785, compound

Procedure

Prepared in analogy to that of Example 5(a) from 2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester and 3,4-difluorobenzyl bromide. The title compound, ESI MS (m/z): 280 (M+H)+.

Sources & evidence

ORD record
ord-54c96bfa9fa74b54b849a8ba76f1d48b
Source dataset
uspto-grants-2010_04
Patent number
US07696223B2

Reaction notes

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