Tributylphenyltin → HCID 68428916, compound

HRID 642566Notes

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[N:11]=[C:10](Br)[C:9]2[N:13]=[C:14]([C:16]([CH3:19])([CH3:18])[CH3:17])[S:15][C:8]=2[C:7]=1[OH:20])=[O:5])[CH3:2].C([Sn](CCCC)(CCCC)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)CCC>>[CH2:1]([O:3][C:4]([C:6]1[N:11]=[C:10]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:9]2[N:13]=[C:14]([C:16]([CH3:19])([CH3:18])[CH3:17])[S:15][C:8]=2[C:7]=1[OH:20])=[O:5])[CH3:2]

Participants

Reactant 2

HCID 607632Tributylphenyltin

HCID 86617377HCID 86617377, compound

Product 1

HCID 68428916HCID 68428916, compound

Procedure

The title compound was prepared from 4-bromo-2-tert-butyl-7-hydroxy-thiazolo[4,5-c]pyridine-6-carboxylic acid ethyl ester and tributylphenyl tin under conditions analogous to the experimental procedure found in example 169(a). MS (ESI+): m/z 412.0 (M+1).

Sources & evidence

ORD record: ord-323afe36cbf84c93a878f6d3da51720c
Source dataset: uspto-grants-2010_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07696223B2

Reaction notes

Loading…