1-(Bromomethyl)naphthalene → HCID 58900212, compound

HRID 642608Notes

Reaction equation

HRID 642608 reaction equation
C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([C:13]=1[Cl:14])=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:4].Br[CH2:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][CH:18]=1>>[Cl:14][C:13]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]([CH2:16][C:17]2[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH:20]=[CH:19][CH:18]=2)[C:5]=1[C:3]([OH:2])=[O:4]

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 1481914methyl 3-chloro-1H-indole-2-carboxylate

Product 1

HCID 58900212HCID 58900212, compound

Procedure

Using general procedure B, 3-chloro-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 334.3 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-704584a73b1a422c98de3958d6c7b1c7
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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