1-(Bromomethyl)naphthalene → HCID 58900236, compound

HRID 642609Notes

Reaction equation

HRID 642609 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([C:14]=1[O:15][CH3:16])=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:18][C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=[CH:21][CH:20]=1>>[CH3:16][O:15][C:14]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]([CH2:18][C:19]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=2)[C:6]=1[C:4]([OH:3])=[O:5]

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 12490854HCID 12490854, compound

Product 1

HCID 58900236HCID 58900236, compound

Procedure

Using general procedure B, 3-methoxy-1H-indole-2-carboxylic acid ethyl ester (Lit. 1) was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 332.1 ([M+H]+).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-6554830d095049baa55a89804e6b24a4
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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