1-(Bromomethyl)naphthalene → HCID 58900251, compound

HRID 642615Notes

Reaction equation

HRID 642615 reaction equation
C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([C:13]=1[CH2:14][NH:15][C:16](=[O:24])[C:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=1)=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:4].Br[CH2:26][C:27]1[C:36]2[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH:30]=[CH:29][CH:28]=1>>[CH3:23][C:20]1[CH:19]=[CH:18][C:17]([C:16]([NH:15][CH2:14][C:13]2[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[N:6]([CH2:26][C:27]3[C:36]4[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=4)[CH:30]=[CH:29][CH:28]=3)[C:5]=2[C:3]([OH:2])=[O:4])=[O:24])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 1475139HCID 1475139, compound

Product 1

HCID 58900251HCID 58900251, compound

Procedure

Using general procedure B, 3-[(4-methyl-benzoylamino)-methyl]-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 447.3 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-784dd172eaa8484c8d094fb0e259200b
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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