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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642617Generated: October 26, 2026

1-(Bromomethyl)naphthalene → 4-Methyl-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/642617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)naphthaleneHCID 137844—
Reactantmethyl 4-methyl-1H-indole-2-carboxylateHCID 4714967—
Product4-Methyl-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acidHCID 58900276—

Reaction Steps

Using general procedure B, 4-methyl-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a pale yellow solid. MS: 314.1 ([M−H]−).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696240B2
Source datasetuspto-grants-2010_04
ORD IDord-920fa18dfa98483ab38d44d82c76b9ca
Source noteuspto-grants-2010_04