1-(Bromomethyl)naphthalene → HCID 58900274, compound

HRID 642620Notes

Reaction equation

HRID 642620 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([F:15])=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[CH:20][CH:19]=1>>[F:15][C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:17][C:18]1[C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[CH:21]=[CH:20][CH:19]=1)[C:6]([C:4]([OH:3])=[O:5])=[CH:14]2

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 2727899ethyl 5-fluoro-1H-indole-2-carboxylate

Product 1

HCID 58900274HCID 58900274, compound

Procedure

Using general procedure B, 5-fluoro-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 318.1 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-7f27e08bc9af46c7a318e09175a17224
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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