2-Indolecarboxylic acid, 5-ethyl-, ethyl ester → HCID 58900218, compound

HRID 642624Notes

Reaction equation

HRID 642624 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([CH2:15][CH3:16])=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:18][C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=[CH:21][CH:20]=1>>[CH2:15]([C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:18][C:19]1[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=1)[C:6]([C:4]([OH:3])=[O:5])=[CH:14]2)[CH3:16]

Participants

3

Reactant 2

HCID 376102-Indolecarboxylic acid, 5-ethyl-, ethyl esterHCID 1378441-(Bromomethyl)naphthalene

Product 1

HCID 58900218HCID 58900218, compound

Procedure

Using general procedure B, 5-ethyl-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a pale brown solid. MS: 328.3 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-1a14056d0ef94ed8887993e73bea8bf8
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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