1-(Bromomethyl)naphthalene → HCID 58900242, compound

HRID 642625Notes

Reaction equation

HRID 642625 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][C:11]([CH:15]([CH3:17])[CH3:16])=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:19][C:20]1[C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[CH:23]=[CH:22][CH:21]=1>>[CH:15]([C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:19][C:20]1[C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH:23]=[CH:22][CH:21]=1)[C:6]([C:4]([OH:3])=[O:5])=[CH:14]2)([CH3:16])[CH3:17]

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 4715165ethyl 5-isopropyl-1H-indole-2-carboxylate

Product 1

HCID 58900242HCID 58900242, compound

Procedure

Using general procedure B, 5-isopropyl-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a pale brown solid. MS: 342.0 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-4b7bb0fe19a84aec81d04f1cdf3d9e5b
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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