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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 642627Generated: November 1, 2026

1-(Bromomethyl)naphthalene → 6-Bromo-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/642627

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)naphthaleneHCID 137844—
Reactant6-Bromo-1H-indole-2-carboxylic acid ethyl esterHCID 7009496—
Product6-Bromo-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acidHCID 58900221—

Reaction Steps

Using general procedure B, 6-bromo-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as white solid. MS: 380.1 ([M−H]−).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07696240B2
Source datasetuspto-grants-2010_04
ORD IDord-8f997ceb21de4a05aab43b64a5ddf91c
Source noteuspto-grants-2010_04