1-(Bromomethyl)naphthalene → HCID 58900238, compound

HRID 642629Notes

Reaction equation

HRID 642629 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[CH:9]=2)=[O:5])C.Br[CH2:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[CH:20][CH:19]=1>>[Cl:15][C:10]1[CH:9]=[C:8]2[C:13]([CH:14]=[C:6]([C:4]([OH:3])=[O:5])[N:7]2[CH2:17][C:18]2[C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[CH:21]=[CH:20][CH:19]=2)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 7015027Ethyl 6-chloroindole-2-carboxylate

Product 1

HCID 58900238HCID 58900238, compound

Procedure

Using general procedure B, 6-chloro-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a pale yellow solid. MS: 334.0 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-c1d11cf20d3a4bb895e487ccf91103de
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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