1-(Bromomethyl)naphthalene → HCID 58900219, compound

HRID 642630Notes

Reaction equation

HRID 642630 reaction equation
C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[C:9]([O:14][CH3:15])[CH:8]=2)=[O:4].Br[CH2:17][C:18]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[CH:20][CH:19]=1>>[CH3:15][O:14][C:9]1[CH:8]=[C:7]2[C:12]([CH:13]=[C:5]([C:3]([OH:2])=[O:4])[N:6]2[CH2:17][C:18]2[C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[CH:21]=[CH:20][CH:19]=2)=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 688173Methyl-6-methoxy-2-indolecarboxylate

Product 1

HCID 58900219HCID 58900219, compound

Procedure

Using general procedure B, 6-methoxy-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 330.1 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-75bd5aaaf2624c35a515989e5f181ed5
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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