1-(Bromomethyl)naphthalene → HCID 58900291, compound

HRID 642632Notes

Reaction equation

HRID 642632 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][C:9]=2[O:15][CH3:16])=[O:5])C.Br[CH2:18][C:19]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=[CH:21][CH:20]=1>>[CH3:16][O:15][C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:8]=1[N:7]([CH2:18][C:19]1[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=[CH:21][CH:20]=1)[C:6]([C:4]([OH:3])=[O:5])=[CH:14]2

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 1235154Ethyl 7-methoxy-1H-indole-2-carboxylate

Product 1

HCID 58900291HCID 58900291, compound

Procedure

Using general procedure B, 7-methoxy-1H-indole-2-carboxylic acid ethyl ester (Lit. 6) was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 330.3 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-2e60b0305c7343808737345e303a98e5
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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