1-(Bromomethyl)naphthalene → HCID 58900282, compound

HRID 642633Notes

Reaction equation

HRID 642633 reaction equation
C[O:2][C:3]([C:5]1[NH:6][C:7]2[C:12]([CH:13]=1)=[CH:11][CH:10]=[CH:9][C:8]=2[CH3:14])=[O:4].Br[CH2:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][CH:18]=1>>[CH3:14][C:8]1[CH:9]=[CH:10][CH:11]=[C:12]2[C:7]=1[N:6]([CH2:16][C:17]1[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH:20]=[CH:19][CH:18]=1)[C:5]([C:3]([OH:2])=[O:4])=[CH:13]2

Participants

3

Procedure

Using general procedure B, 7-methyl-1H-indole-2-carboxylic acid methyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 314.3 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-a4d9da807bc542718e4ea5f3fb86ef5e
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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