HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)naphthalene → 5-Fluoro-3-methyl-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)naphthalene | HCID 137844 | — |
| Reactant | ethyl 5-fluoro-3-methyl-1H-indole-2-carboxylate | HCID 930786 | — |
| Product | 5-Fluoro-3-methyl-1-naphthalen-1-ylmethyl-1H-indole-2-carboxylic acid | HCID 58900240 | — |
Reaction Steps
Using general procedure B, 5-fluoro-3-methyl-1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-naphthalene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 332.1 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696240B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-59b153b7548547b2aa524915eae363f4 |
| Source note | uspto-grants-2010_04 |