HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl indole-2-carboxylate → 1-(7-chloro-naphthalen-1-ylmethyl)-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl indole-2-carboxylate | HCID 73125 | — |
| Reactant | 1-(Bromomethyl)-7-chloronaphthalene | HCID 68578095 | — |
| Product | 1-(7-chloro-naphthalen-1-ylmethyl)-1H-indole-2-carboxylic acid | HCID 58900286 | — |
Reaction Steps
Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 1-bromomethyl-7-chloro-naphthalene and the product obtained was hydrolyzed to give 1-(7-chloro-naphthalen-1-ylmethyl)-1H-indole-2-carboxylic acid as a white solid. MS: 334.0 ([M−H]).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696240B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-37082c75f4ca41e1b3b8fdbe0f49fa9e |
| Source note | uspto-grants-2010_04 |