Ethyl indole-2-carboxylate → HCID 58900283, compound

HRID 642655Notes

Reaction equation

HRID 642655 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])C.[Cl:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[C:22]([CH2:26]Cl)=[CH:21][CH:20]=[CH:19]2>>[Cl:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[C:22]([CH2:26][N:7]1[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:14]=[C:6]1[C:4]([OH:3])=[O:5])=[CH:21][CH:20]=[CH:19]2

Participants

3

Reactant 2

HCID 73125Ethyl indole-2-carboxylateHCID 68578058HCID 68578058, compound

Product 1

HCID 58900283HCID 58900283, compound

Procedure

Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 6-chloro-1-chloromethyl-naphthalene (Lit. 14) and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 334.0 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-4ef43b32982740be8f5bd999d5ab50c8
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

Loading…