HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl indole-2-carboxylate → 1-Benzo[b]thiophen-3-ylmethyl-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl indole-2-carboxylate | HCID 73125 | — |
| Reactant | 3-(Chloromethyl)benzo(b)thiophene | HCID 76680 | — |
| Product | 1-Benzo[b]thiophen-3-ylmethyl-1H-indole-2-carboxylic acid | HCID 58900228 | — |
Reaction Steps
Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 3-chloromethyl-benzo[b]thiophene and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 306.4 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696240B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-e319522e64404625a3f038444bb31e67 |
| Source note | uspto-grants-2010_04 |