Ethyl indole-2-carboxylate → HCID 58900272, compound

HRID 642666Notes

Reaction equation

HRID 642666 reaction equation
C([O:3][C:4]([C:6]1[NH:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])C.Br[CH2:16][C:17]1[C:18]2[C:25]([Cl:26])=[CH:24][CH:23]=[CH:22][C:19]=2[S:20][CH:21]=1>>[Cl:26][C:25]1[C:18]2[C:17]([CH2:16][N:7]3[C:8]4[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=4)[CH:14]=[C:6]3[C:4]([OH:3])=[O:5])=[CH:21][S:20][C:19]=2[CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 73125Ethyl indole-2-carboxylateHCID 1239862320896-07-5

Product 1

HCID 58900272HCID 58900272, compound

Procedure

Using general procedure B, 1H-indole-2-carboxylic acid ethyl ester was coupled with 3-bromomethyl-4-chloro-benzo[b]thiophene (Li. 17) and the product obtained was hydrolyzed to give the title compound as a white solid. MS: 340.0 ([M−H]−).

Workup

  1. customthe product obtained

Sources & evidence

ORD record
ord-3af91802925d465e9d0488a6236ab470
Source dataset
uspto-grants-2010_04
Patent number
US07696240B2

Reaction notes

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