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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 64267Generated: October 25, 2026

2'-Nitroacetophenone → 2-(4-(Benzyloxy)phenyl)-7-(2-nitrophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

https://huagongshe.com/reaction/64267

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2'-NitroacetophenoneHCID 11346—
ReactantN-(3-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)acetamideHCID 117668104—
ReactantHCID 178509390HCID 178509390—
Product2-(4-(Benzyloxy)phenyl)-7-(2-nitrophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrileHCID 117668318—

Reaction Steps

The desired product was prepared from 1-(2-nitrophenyl)ethanone and 5-amino-3-(4-(benzyloxy)phenyl)-1H-pyrazole-4-carbonitrile according to the procedures similar to those (step 4 and step 5) for N-(3-(3-cyano-2-(4-phenoxyphenyl) pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)acetamide under appropriate conditions recognized by one of ordinary skill in the art.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447106B2
Source datasetuspto-grants-2016_09
ORD IDord-8a958c23da9744c2bb5f3cabfb13548c
Source noteuspto-grants-2016_09