HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Difluoroazetidine hydrochloride → HCID 58900266, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Difluoroazetidine hydrochloride | HCID 2758247 | — |
| Reactant | HCID 86613188 | HCID 86613188 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 58900266 | HCID 58900266 | — |
Reaction Steps
6-Fluoro-9-naphthalen-1-ylmethyl-4,9-dihydro-pyrano[3,4-b]indole-1,3-dione (from Example 68.1.) was ring opened with 3,3-difluoro-azetidine hydrochloride and NEt3 at 22° C. to give the title compound as a white solid. MS: 450.9 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07696240B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-8a85bc699a2646b09485c947c575e9b5 |
| Source note | uspto-grants-2010_04 |