methyl 6H-thieno[2,3-b]pyrrole-5-carboxylate → HCID 68580509, compound

Participants

Reaction Steps

Using general procedure B, methyl 6H-thieno[2,3-b]pyrrole-5-carboxylate was coupled with 1-bromomethyl-7-fluoro-naphthalene (from Example 49.3.) to give 6-(7-fluoro-naphthalen-1-ylmethyl)-6H-thieno[2,3-b]pyrrole-5-carboxylic acid methyl ester which was hydrolyzed as described in the general procedure B (Exp. 2.2) to give the title compound as a white solid. MS: 324.5 ([M−H]−).

Provenance & Evidence