1-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzene → HCID 16755224, compound

HRID 642799Notes

Reaction equation

HRID 642799 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([C:9]([F:12])([F:11])[F:10])[CH:8]=1)[NH2:5].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]=[C:21]=[S:22])=[CH:16][C:15]=1[C:23]([F:26])([F:25])[F:24]>>[F:1][C:2]1[CH:3]=[C:4]([NH:5][C:21]([NH:20][C:17]2[CH:18]=[CH:19][C:14]([Cl:13])=[C:15]([C:23]([F:26])([F:24])[F:25])[CH:16]=2)=[S:22])[CH:6]=[C:7]([C:9]([F:10])([F:11])[F:12])[CH:8]=1

Participants

3

Reactant 2

HCID 5200261-Chloro-4-isothiocyanato-2-(trifluoromethyl)benzeneHCID 27359133-Amino-5-fluorobenzotrifluoride

Product 1

HCID 16755224HCID 16755224, compound

Procedure

The title compound was synthesized according to the procedure used in example 2 starting with 3-Fluoro-5-(trifluoromethyl)-aniline and 4-Chloro-3-(trifluoromethyl)-phenylisothiocyanate. Yield: 98 mg (47%).

Sources & evidence

ORD record
ord-e41e746f8ed74d67b13b8749eedf5f72
Source dataset
uspto-grants-2010_04
Patent number
US07696249B2

Reaction notes

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