56970-24-2 → Racemic 3-{4-[1-(2-methoxy-biphenyl-4-ylamino)-hexyl]-benzoylamino}-propionic acid

HRID 642811Notes

Reaction equation

HRID 642811 reaction equation
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][NH:6][C:7](=[O:21])[C:8]1[CH:13]=[CH:12][C:11]([C:14](=O)[CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[CH:10][CH:9]=1.[CH3:23][O:24][C:25]1[CH:30]=[C:29]([NH2:31])[CH:28]=[CH:27][C:26]=1[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH3:23][O:24][C:25]1[CH:30]=[C:29]([NH:31][CH:14]([C:11]2[CH:12]=[CH:13][C:8]([C:7]([NH:6][CH2:5][CH2:4][C:3]([OH:2])=[O:22])=[O:21])=[CH:9][CH:10]=2)[CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH:28]=[CH:27][C:26]=1[C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=1

Participants

3

Reactant 2

HCID 52177356970-24-2HCID 67484898HCID 67484898, compound

Product 1

HCID 24760124Racemic 3-{4-[1-(2-methoxy-biphenyl-4-ylamino)-hexyl]-benzoylamino}-propionic acid

Procedure

The title compound is prepared by the general method exemplified in Example 1 using 3-(4-hexanoyl-benzoylamino)-propionic acid methyl ester (Preparation 5) and 2-methoxy-biphenyl-4-ylamine as starting materials. MS (ES): 475.2 [M+H]+.

Sources & evidence

ORD record
ord-1bf802784377494d86e0e310a333256c
Source dataset
uspto-grants-2010_04
Patent number
US07696248B2

Reaction notes

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