Acetic Acid → HCID 178432158, compound

Participants

Reaction Steps

A solution of 120 mg (0.16 mmol) (R)-1-(3,4-diamino-5-methyl-benzyl)-2-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-2-oxo-ethyl 4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carboxylate were refluxed in 2 mL AcOH for 2 h and then evaporated down i.vac. The residue was purified by HPLC, the fractions containing the product were combined and lyophilised.

Provenance & Evidence