O-Phenylenediamine → 2-(4-Bromophenyl)-3-phenylquinoxaline

Participants

Reaction Steps

8.2 g (29 mmol) of 1-(4-bromophenyl)-2-phenylethanedione, 3.1 g (31 mmol) of o-phenylenediamine, and 100 mL of ethanol were placed into a 300-mL flask, and the mixture was refluxed for 2 hours. After the reaction, the precipitated solid was collected by suction filtration. The collected solid washed with ethanol and dried. 7.3 g of a light-yellow solid was obtained as the target substrate in 69% yield.

Provenance & Evidence