Hydrochloric Acid → HCID 131728057, compound

Participants

Reaction Conditions

Reaction Steps

A solution of Example 18C (0.11 g, 0.18 mmol) in THF (2 mL) was treated with 4N HCl (0.3 mL), stirred at 60° C. for 3 hrs and cooled to room temperature. The mixture was concentrated, neutralized with 10% sodium bicarbonate, and extracted with ethyl acetate, the organic layer washed with brine, dried over sodium sulfate, filtered and the solvents were evaporated to give 92 mg (100%) of the title compound.

Provenance & Evidence