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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 64315Generated: October 25, 2026

2-Bromo-1-(3-nitrophenyl)ethan-1-one → HCID 178513496, compound

https://huagongshe.com/reaction/64315

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(3-nitrophenyl)ethan-1-oneHCID 75213—
ReactantHCID 178513497HCID 178513497—
SolventEthanolHCID 702—
ProductHCID 178513496HCID 17851349611.4%

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carboxamide (29.4 mg, 0.1 mmol) and 2-bromo-1-(3-nitrophenyl)ethanone (24.4 mg, 0.1 mmol) in EtOH (2 mL) was stirred at 80° C. for 16 hr. The mixture was filtered to afford 5 mg of crude 2-(3-nitrophenyl)-6-(4-phenoxyphenyl)-1H-imidazo[1,2-b]pyrazole-7-carboxamide as a yellow solid. MS (ESI) m/e [M+1]+ 440.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447106B2
Source datasetuspto-grants-2016_09
ORD IDord-ee2d4ce594704a0985377a363f5590cf
Source noteuspto-grants-2016_09