Chloromethyl Methyl Ether → HCID 23116092, compound

Temperature

15 °C

A 47.50 g quantity of ethyldimethylamine (reagent, product of Tokyo Kasei Co., Ltd.) was dissolved in 300 g of dehydrated acetone(reagent, Wako Pure Chemical Ind. Ltd.), followed by nitrogen replacement. Over a period of 1 hour, 52.30 g of chloromethyl methyl ether (reagent, product of Tokyo Kasei Co., Ltd., distilled one) was added dropwise to the solution at 5° C. The mixture was stirred at lower than 15° C. for 5 hour to complete the reaction. The reaction mixture was cooled to 5° C. and was filtered under nitrogen atmosphere. The solids obtained were washed with 150 g of acetone and then dried in a vacuum, giving 85.90 g of the desired product (white solid).

1. customthe reaction
2. temperatureThe reaction mixture was cooled to 5° C.
3. filtrationwas filtered under nitrogen atmosphere
4. customThe solids obtained
5. washwere washed with 150 g of acetone
6. customdried in a vacuum

ORD record

ord-32a293c673644911b63bae8fada77028

Source dataset

uspto-grants-2010_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07700243B2