HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 85875172, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Potassium Bicarbonate | HCID 516893 | — |
| Reactant | 6-(2-chloroacetamido)hexanoic acid | HCID 2104051 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 85875172 | HCID 85875172 | — |
Reaction Steps
2.8 g (20 mmol) potassium hydrogen carbonate were added to 8.3 g (40 mmol) 6-(chloracetamido) hexanoic acid dissolved in 25 ml water. 3.2 g (48 mmol) potassium cyanide was then added to the clear solution which was cooled on ice. The reaction mixture was stirred for 17 hours and was then acidified with HCl (2N). The residue after extraction was purified by chromatography (silica gel, solvent: ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700306B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-89a04f08e9d6410690e8f9eb18855139 |
| Source note | uspto-grants-2010_04 |