3Alpha,7Alpha,12Alpha-trihydroxy-5Beta-cholestan-26-oic acid → Tetrahydrocannabinol

HRID 643215Notes

Reaction equation

HRID 643215 reaction equation
C[C@@H]([C@@H]1[C@@]2(C)[C@@H](O)C[C@@H]3[C@@]4(C)CC[C@@H](O)C[C@H]4C[C@@H](O)[C@H]3[C@@H]2CC1)CCCC(C(O)=O)C.[CH3:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]1[CH:39]=[C:40]([OH:55])[C:41]2[C@@H:47]3[CH:48]=[C:49]([CH3:52])[CH2:50][CH2:51][C@H:46]3[C:45]([CH3:54])([CH3:53])[O:44][C:42]=2[CH:43]=1.C(=O)=O>>[CH3:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]1[CH:39]=[C:40]([OH:55])[C:41]2[C@@H:47]3[CH:48]=[C:49]([CH3:52])[CH2:50][CH2:51][C@H:46]3[C:45]([CH3:54])([CH3:53])[O:44][C:42]=2[CH:43]=1

Participants

3

Reactant 2

HCID 1223123Alpha,7Alpha,12Alpha-trihydroxy-5Beta-cholestan-26-oic acidHCID 131728058Thc CO2

Product 1

HCID 16078Tetrahydrocannabinol

Procedure

Material slowly decarboxylates in solution Δ9 THCA→Δ9 THC+CO2

Sources & evidence

ORD record
ord-e6eb15e2bead4f1f95082c7a4ec79f61
Source dataset
uspto-grants-2010_04
Patent number
US07700368B2

Reaction notes

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