Water → 2,5-Bis(perfluorobutyl)-p-xylene

Participants

Reaction Steps

A solution of C4F9I (0.96 mL, 5.6 mmol) was added dropwise over 10 min to a stirred mixture of 2,5-diiodo-ρ-xylene (0.5 g, 1.4 mmol), copper powder (1.4 g, 22.4 mmol) in DMSO (10 mL) at 130° C. The reaction mixture was subsequently stirred for a further 24 h at this temperature. After cooling to room temperature, it was poured into a beaker containing dichloromethane (30 mL) and water (30 mL). After filtering, the organic layer was separated, washed with water (3×30 mL) and dried over MgSO4. The residue was purified by column chromatography (hexane as eluant) to give the product 8 as a white solid (553 mg, 73%).

Provenance & Evidence