HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-6-methoxycarbonylnaphthalene → (6-Bromonaphthalen-2-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-6-methoxycarbonylnaphthalene | HCID 854134 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (6-Bromonaphthalen-2-yl)methanol | HCID 13473070 | — |
Reaction Steps
Methyl-6-bromo-2-naphtoate (25 g, 94.3 mmol) was reduced with lithiumaluminiumhydride (5.36 g, 141.4 mmol) in tetrahydrofuran (200 ml). The crystalline product was recrystallized from ethanol (96%). Yield 15.84 g (70.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07700596B2 |
| Source dataset | uspto-grants-2010_04 |
| ORD ID | ord-da364bd7ed204dd4bf273626c15fda0b |
| Source note | uspto-grants-2010_04 |