Phenyl isocyanate → N-[3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl]-N'-phenylurea

Participants

Reaction Steps

Phenyl isocyanate (0.075 g, 0.63 mmol) was added to a stirred solution of 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenylamine (0.025 g, 0.076 mmol) in 5 mL of ACN at room temperature. The reaction mixture was stirred for 3 hours and concentrated. The residue was purified by silica gel chromatography using 5-50% EtOAc/hexanes as eluent to provide 0.025 g of the title compound as a gray solid. HRMS (ESI, [M+H]+) 451.1310.

Provenance & Evidence