2-Chloro-3-(trifluoromethyl)benzaldehyde → HCID 11855894, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1.[Cl:25][C:26]1[C:33]([C:34]([F:37])([F:36])[F:35])=[CH:32][CH:31]=[CH:30][C:27]=1[CH:28]=O>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH:24][CH2:28][C:27]2[CH:30]=[CH:31][CH:32]=[C:33]([C:34]([F:35])([F:37])[F:36])[C:26]=2[Cl:25])[CH:21]=[CH:22][CH:23]=1Participants
3
Procedure
The title compound was prepared from 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenylamine and 2-chloro-3-trifluoromethylbenzaldehyde according to the procedure of Step 5 Example 6. MS (ESI) m/z 522.
Sources & evidence
- ORD record
- ord-cf54fe679f3445e394428faa9b633be2
- Source dataset
- uspto-grants-2010_04
- Patent number
- US07700595B2
Reaction notes
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