3-(8-Chloro-3-phenyl-cinnolin-4-yl)-phenylamine → Methyl 2-[4-({[3-(8-chloro-3-phenylcinnolin-4-yl)phenyl]amino}methyl)phenyl]-2-methylpropanoate

HRID 643308Notes

Reaction equation

HRID 643308 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1.[CH3:25][O:26][C:27](=[O:39])[C:28]([C:31]1[CH:36]=[CH:35][C:34]([CH:37]=O)=[CH:33][CH:32]=1)([CH3:30])[CH3:29]>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[N:9][C:8]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[C:7]2[C:18]1[CH:19]=[C:20]([NH:24][CH2:37][C:34]2[CH:33]=[CH:32][C:31]([C:28]([CH3:30])([CH3:29])[C:27]([O:26][CH3:25])=[O:39])=[CH:36][CH:35]=2)[CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 118566993-(8-Chloro-3-phenyl-cinnolin-4-yl)-phenylamineHCID 25111210Methyl 2-(4-formylphenyl)-2-methylpropanoate

Product 1

HCID 11855893Methyl 2-[4-({[3-(8-chloro-3-phenylcinnolin-4-yl)phenyl]amino}methyl)phenyl]-2-methylpropanoate

Procedure

The title compound was prepared from 3-(8-chloro-3-phenyl-cinnolin-4-yl)-phenylamine and 2-(4-formyl-phenyl)-2-methyl-propionic acid methyl ester according to the procedure of Step 5 Example 6. MS (ES) m/z 522.2.

Sources & evidence

ORD record
ord-69db4edc18294b2c8c05f428aae050aa
Source dataset
uspto-grants-2010_04
Patent number
US07700595B2

Reaction notes

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