2-Chloro-3-(trifluoromethyl)benzaldehyde → [3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chloro-3-(trifluoromethyl)benzyl]amine

HRID 643313Notes

Reaction equation

HRID 643313 reaction equation
[CH2:1]([C:8]1[N:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:26][C:27]1[C:34]([C:35]([F:38])([F:37])[F:36])=[CH:33][CH:32]=[CH:31][C:28]=1[CH:29]=O>>[CH2:1]([C:8]1[N:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:29][C:28]3[CH:31]=[CH:32][CH:33]=[C:34]([C:35]([F:36])([F:38])[F:37])[C:27]=3[Cl:26])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 27366722-Chloro-3-(trifluoromethyl)benzaldehydeHCID 11855621[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]amine

Product 1

HCID 11855620[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chloro-3-(trifluoromethyl)benzyl]amine

Procedure

The title compound was prepared from [3-(3-benzyl-8-chlorocinnolin-4-yl)phenyl]amine and 2-chloro-3-trifluoromethylbenzaldehyde according to the procedure of Step 5 Example 6. MS (ESI) m/z 538.

Sources & evidence

ORD record
ord-d1ad659f68a6470083b75a2e0dbe6312
Source dataset
uspto-grants-2010_04
Patent number
US07700595B2

Reaction notes

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