[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]amine → [3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-chloro-2-(trifluoromethyl)benzyl]amine

HRID 643315Notes

Reaction equation

HRID 643315 reaction equation
[CH2:1]([C:8]1[N:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH2:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:26][C:27]1[CH:28]=[CH:29][C:30]([C:35]([F:38])([F:37])[F:36])=[C:31]([CH:34]=1)[CH:32]=O>>[CH2:1]([C:8]1[N:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([NH:24][CH2:32][C:31]3[CH:34]=[C:27]([Cl:26])[CH:28]=[CH:29][C:30]=3[C:35]([F:37])([F:36])[F:38])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[Cl:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 11855621[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]amineHCID 177507585-Chloro-2-(trifluoromethyl)benzaldehyde

Product 1

HCID 11855354[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-chloro-2-(trifluoromethyl)benzyl]amine

Procedure

The title compound was prepared from [3-(3-benzyl-8-chlorocinnolin-4-yl)phenyl]amine and 5-chloro-2-trifluoromethylbenzaldehyde according to the procedure of Step 5 Example 6. MS (ESI) m/z 538.

Sources & evidence

ORD record
ord-c7723d0373ba4bd2abe76f47e726d0d6
Source dataset
uspto-grants-2010_04
Patent number
US07700595B2

Reaction notes

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